Impact of personal genomic risk information on melanoma prevention behaviors and psychological outcomes: a randomized controlled trial
Amelia K. Smit e outros, 2021 · Genetics in Medicine
Providing personalized melanoma polygenic risk information alongside telephone genetic counseling reduced self-reported sunburn incidence at 12 months by 28%.
Estimativa · Sunburn incidence in past month, relative risk
0,720 [0,540; 0,960]
relative risk
p = 0.02
- Desenho
- Experimento aleatório. Parallel-group open randomized controlled trial
- População
- Australians of European ancestry aged 18–69 without personal history of melanoma recruited via the Medicare database
- Amostra
- 1.025 · adults randomized (973 completed 12-month follow-up questionnaire)
Onde está o número
RESULTS > Secondary outcomes > Sunburn; Results, Secondary outcomes, Sunburn, first sentence
The intervention reduced self-reported sunburn incidence in the intervention versus control group by 28% (relative risk 0.72, 95% CI: 0.54, 0.96; p = 0.02) at 12 months
Contexto
What changed: Participants received a personalized booklet reporting polygenic melanoma risk based on 40 variants, a genetic counseling phone call, and standard education. Comparison: Control group receiving an educational booklet only. Limits: Low population consent rate (3.4%) and self-reported sunburn outcome.
Caminho no grafo
- FamíliaInformação e persuasão
- TipoCampanha de informação
- EixoSaúde
MAGI só cita evidência deste instrumento
Lugares do estudo
- Australia · País · AU
- Licença
- CC-BY
- Revisão
- Extraído por máquina, não revisadoExtraído por: gemini-3.8-flash, 2026-10-23